Exploring Estradiol, Pulse Wave Velocity, and PTSD in Trauma-Exposed Women

In this episode of the APS Publications Podcast, we’re joined by coauthors Chasity Corbin, Chowdhury Ibtida Tahmin, and Ida T. Fonkoue to discuss their research titled "Estradiol levels are differentially associated with pulse wave velocity in trauma-exposed premenopausal women with and without PTSD." The study investigates how serum estradiol (E2) levels influence pulse wave velocity (PWV) in premenopausal women exposed to trauma, with a particular focus on the impact of posttraumatic stress disorder (PTSD). The researchers discovered that E2 levels predicted PWV only in women without PTSD, even after accounting for factors like menstrual cycle phase, age, body mass index, diastolic blood pressure, and PTSD symptom severity. Additionally, the study found that E2 levels were significantly lower in women with PTSD. Tune in as our guests dive into the details of this important study.

 

Estradiol levels are differentially associated with pulse wave velocity in trauma-exposed premenopausal women with and without PTSD

Chasity Corbin, Chowdhury Ibtida Tahmin, Chowdhury Tasnova Tahsin, Zynab Ahmed, Redeat Wattero, Azhaar Mohamed, Susan B. Racette, Daniel Duprez, and Ida T. Fonkoue

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2025 328:3, R235-R241