APS Publications Podcast

Interorgan Insights: Role of Diet and Exercise Interventions for MAFLD Outcomes

In this podcast, coauthors Maria Magdalena Quetglas-Llabrés and Manuel Jiménez-García discuss their recently published article, ‘Effects of Combining Exercise and Dietary Shifts on Motor Coordination and Oxidative Markers in a High-Fat Diet Model in Rats.' The article investigated the effect of exercise, alone or with dietary modifications, on high fat diet–induced outcomes in rats of both sexes. Authors overview the methodological approach and discuss key takeaways and next steps.  

Effects of Combining Exercise and Dietary Shifts on Motor Coordination and Oxidative Markers in a High-Fat Diet Model in Rats

Manuel Jiménez-García, Maria Magdalena Quetglas-Llabrés, Maria Del Mar Ribas-Taberner, Antoni Sureda-Gomila, David Moranta-Mesquida, Silvia Tejada-Gavela

Comprehensive Physiology 2025;15(6):e70074 

https://doi.org/10.1002/cph4.70074 

The practical skills passport: a co-curricular program to enhance lab skills confidence in undergraduate neuroscience and biology students

In this episode of the APS Publications Podcast, featuring Advances in Physiology Education, coauthors Anna Smith, Fran der Weduwen, and Thomas Powell discuss their recently published Illuminations paper “The practical skills passport: a co-curricular program to enhance lab skills confidence in undergraduate neuroscience and biology students”. The COVID-19 pandemic limited in-person lab opportunities, impacting students’ skills and confidence. This episode explores the development, implementation, and evaluation of a co-curricular lab skills program designed to help students regain confidence during their return to in-person learning. Findings show that participation in the program had a positive impact on student lab confidence.

 

The practical skills passport: a co-curricular program to enhance lab skills confidence in undergraduate neuroscience and biology students

Anna E. Smith, Fran der Weduwen, Thomas Powell, and Gayle Doherty

Advances in Physiology Education 2025 49:3, 696-703

Misconception about the application of Dalton’s Law in respiratory physiology

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, Prof. S. Mehran Hosseini discusses the study, “Misconception about the application of Dalton’s Law in respiratory physiology.”

Dalton’s Law may provide a good example for students to highlight the existence of misconceptions and their effect on gaining new knowledge. The awareness of students about this misconception may improve their learning styles.

Misconception about the application of Dalton’s Law in respiratory physiology

S. Mehran Hosseini

Advances in Physiology Education 2025 49:3, 646-650

Connecting Genes to Physiology: The First 25 Years of Physiological Genomics

In this special episode of the APS Publications Podcast, the founding of Physiological Genomics is discussed in a series of interviews with Drs. Allen W. Cowley, Jr., Bina Joe, and Hilary Coller. These interviews were organized and conducted in September 2025 by Oluwatosin Mautin Akinola (PhD candidate in Molecular Medicine at the University of Toledo, Toledo, OH, United States; https://www.researchgate.net/profile/Oluwatosin-Akinola-2). Full videos of these interviews are available as Supplemental Material in the article.

Joe B, Cowley AW, Garrett MR, Kriegel AJ, Prokop JW, Lee EC, Akinola OM, Coller HA. Connecting Genes to Physiology: The First 25 Years of Physiological Genomics. Physiol Genomics. 2025 Oct 29. doi: 10.1152/physiolgenomics.00207.2025. PMID: 41159925.

Enhancing auditory physiology: simulating unilateral conduction defects to improve understanding of Rinne’s and Weber’s tests

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, Dr. Raju Suresh Kumar discusses a novel, hands-on simulation designed to teach auditory physiology. By experiencing unilateral conductive hearing loss, students gain deeper insight into auditory masking and sound lateralization. This simple, cost-effective method enhances conceptual understanding and clinical skills, offering strong potential for integration into medical education.

Enhancing auditory physiology: simulating unilateral conduction defects to improve understanding of Rinne’s and Weber’s tests

Raju Suresh Kumar, M. Ganesh Kamath, Rekha Prabhu, and Mohamed Eldigire Ahmed

Advances in Physiology Education 2025 49:3, 689-695

Interorgan Insights: Alcohol-Induced Pathophysiological Outcomes

In this podcast, coauthors Liz Simon, Flavia Souza-Smith, Megan Donovan, Eden Gallegos, Kaitlin Couvillon, and Patricia Molina summarize their recently published review article, "Physiological Mechanisms Vulnerable to Alcohol-Induced Alterations: Role in Chronic Comorbidities." The article describes alcohol's multi-systemic physiological effects on the gastrointestinal, cardiovascular, and immune systems, as well as on energy metabolism that contribute to multiorgan injury and disease burden.

 

Physiological Mechanisms Vulnerable to Alcohol-Induced Alterations: Role in Chronic Comorbidities

Liz Simon, Kaitlin E. Couvillion, Meagan E. Donovan, Eden M. Gallegos, Flavia M. Souza-Smith, Patricia E. Molina

Comprehensive Physiology 2025 15:5, e70057 

 https://doi.org/10.1002/cph4.70057

Interorgan Insights: Multi-Organ-On-Chip System to Study Interorgan Communication

In this podcast, coauthors Simon D. Pouwels and Brady Rae discuss their recently published research article, "Interorgan Communication Between Lung and Colorectal Epithelial Cells Studied Using a Novel Multi-Organ-On-Chip System." The article describes development of a novel unidirectional millifluidic multi-organ-on-chip device to study the communication between human lung epithelial cells and colorectal cells following a toxic stimulus. Authors additionally discuss the versatility of the device to study communication across other cell types.  

 

Interorgan Communication Between Lung and Colorectal Epithelial Cells Studied Using a Novel Multi-Organ-On-Chip System

Brady Rae, Verena Bood, Hye-Jin Dijk, Gwenda F. Vasse, Barbro N. Melgert, Anika Nagelkerke, Janette K. Burgess, Dirk-Jan Slebos, Irene H. Heijink, Simon D. Pouwels

Comprehensive Physiology 2025 15:5, e70051

https://doi.org/10.1002/cph4.70051

In Vivo Drosophila Model of CS-induced COPD Phenotypes

In this episode of the APS Publications Podcast, featuring an article from AJP–Regulatory, Integrative and Comparative Physiology, author Periklis Marnas discusses inhalation exposure of adult D. melanogaster to cigarette smoke and changes in physiological parameters and the expression of COPD-associated orthologous genes. The study found that transcriptomic responses were more profound in females, indicating sex-specific responses to inhaled toxicants. Furthermore, enrichment analyses of the differentially expressed genes in females pointed to biomolecules associated with response to nicotine and detoxification. D. melanogaster thus provides a powerful model system to test the efficacy of new potential drugs for COPD treatment.

 

Marnas P, Lüpold S, Giannakou L, Giannopoulos AS, Hatzoglou C, Gourgoulianis KI, Zarogiannis SG, Rouka E. Modeling COPD in Drosophila melanogaster by cigarette smoke inhalation: functional changes and alterations in the expression of COPD-relevant orthologous genes. Am J Physiol Regul Integr Comp Physiol. 2025 Jul 1;329(1):R13-R19. https://doi.org/10.1152/ajpregu.00056.2025